Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II

Membrane-bound cGMP-dependent protein kinase (PKG) II is a key regulator of bone growth, renin secretion, and memory formation. Despite its crucial physiological roles, little is known about its cyclic nucleotide selectivity mechanism due to a lack of structural information. Here, we find that the C...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Campbell, James C., Kim, Jeong Joo, Li, Kevin Y., Huang, Gilbert Y., Reger, Albert S., Matsuda, Shinya, Sankaran, Banumathi, Link, Todd M., Yuasa, Keizo, Ladbury, John E., Casteel, Darren E., Kim, Choel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786703/
https://ncbi.nlm.nih.gov/pubmed/26769964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691303
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