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The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins

As a first-line vertebrate immune defense, the polymeric immunoglobulin receptor (pIgR) transports polymeric IgA and IgM across epithelia to mucosal secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretory antibodies, or when unliganded, binds and excludes...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Stadtmueller, Beth M, Huey-Tubman, Kathryn E, López, Carlos J, Yang, Zhongyu, Hubbell, Wayne L, Bjorkman, Pamela J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786434/
https://ncbi.nlm.nih.gov/pubmed/26943617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10640
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