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Biophysical and biochemical characterization of avian secretory component provides structural insights into the evolution of the polymeric Ig receptor

The polymeric immunoglobulin receptor (pIgR) transports polymeric antibodies across epithelia to the mucosa, where proteolytic cleavage releases the ectodomain (secretory component; SC) as an integral component of secretory antibodies, or as an unliganded protein that can mediate interactions with b...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Stadtmueller, Beth M., Yang, Zhongyu, Huey-Tubman, Kathryn E., Roberts-Mataric, Helena, Hubbell, Wayne L., Bjorkman, Pamela J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976031/
https://ncbi.nlm.nih.gov/pubmed/27412418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600463
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