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Biophysical and biochemical characterization of avian secretory component provides structural insights into the evolution of the polymeric Ig receptor

The polymeric immunoglobulin receptor (pIgR) transports polymeric antibodies across epithelia to the mucosa, where proteolytic cleavage releases the ectodomain (secretory component; SC) as an integral component of secretory antibodies, or as an unliganded protein that can mediate interactions with b...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Stadtmueller, Beth M., Yang, Zhongyu, Huey-Tubman, Kathryn E., Roberts-Mataric, Helena, Hubbell, Wayne L., Bjorkman, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976031/
https://ncbi.nlm.nih.gov/pubmed/27412418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600463
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