Absence of Epithelial Immunoglobulin a Transport, with Increased Mucosal Leakiness, in Polymeric Immunoglobulin Receptor/Secretory Component–Deficient Mice

Mucosal surfaces are protected specifically by secretory immunoglobulin A (SIgA) and SIgM generated through external translocation of locally produced dimeric IgA and pentameric IgM. Their active transport is mediated by the epithelial polymeric Ig receptor (pIgR), also called the transmembrane secr...

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Main Authors: Johansen, Finn-Eirik, Pekna, Marcela, Norderhaug, Inger Natvig, Haneberg, Bjørn, Hietala, Max Albert, Krajci, Peter, Betsholtz, Christer, Brandtzaeg, Per
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195652/
https://ncbi.nlm.nih.gov/pubmed/10510081
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