Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia

Streptococcus (S.) pneumoniae is the most common causative pathogen in community-acquired pneumonia. Coagulation and inflammation interact in the host response to infection. Tissue factor pathway inhibitor (TFPI) is a natural anticoagulant protein that inhibits tissue factor (TF), the main activator...

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Pubblicato in:Thromb Haemost
Autori principali: van den Boogaard, Florry E., Veer, Cornells van't, Roelofs, Joris J. T. H., Meijers, Joost C. M., Schultz, Marcus J., Broze, George, van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786014/
https://ncbi.nlm.nih.gov/pubmed/25832548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-12-1053
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