Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study

INTRODUCTION: Streptococcus (S.) pneumoniae is the most common cause of community-acquired pneumonia. The factor V Leiden (FVL) mutation results in resistance of activated FV to inactivation by activated protein C and thereby in a prothrombotic phenotype. Human heterozygous FVL carriers have been re...

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Autori principali: Schouten, Marcel, van't Veer, Cornelis, Roelofs, Joris JTH, Levi, Marcel, van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945128/
https://ncbi.nlm.nih.gov/pubmed/20682036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9213
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