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Switching desaturase enzyme specificity by alternate subcellular targeting

The functionality, substrate specificity, and regiospecificity of enzymes typically evolve by the accumulation of mutations in the catalytic portion of the enzyme until new properties arise. However, emerging evidence suggests enzyme functionality can also be influenced by metabolic context. When th...

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Detalhes bibliográficos
Main Authors: Heilmann, Ingo, Pidkowich, Mark S., Girke, Thomas, Shanklin, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478599/
https://ncbi.nlm.nih.gov/pubmed/15240892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402200101
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