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Switching desaturase enzyme specificity by alternate subcellular targeting

The functionality, substrate specificity, and regiospecificity of enzymes typically evolve by the accumulation of mutations in the catalytic portion of the enzyme until new properties arise. However, emerging evidence suggests enzyme functionality can also be influenced by metabolic context. When th...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Heilmann, Ingo, Pidkowich, Mark S., Girke, Thomas, Shanklin, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15240892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402200101
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