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Switching desaturase enzyme specificity by alternate subcellular targeting

The functionality, substrate specificity, and regiospecificity of enzymes typically evolve by the accumulation of mutations in the catalytic portion of the enzyme until new properties arise. However, emerging evidence suggests enzyme functionality can also be influenced by metabolic context. When th...

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Библиографические подробности
Главные авторы: Heilmann, Ingo, Pidkowich, Mark S., Girke, Thomas, Shanklin, John
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC478599/
https://ncbi.nlm.nih.gov/pubmed/15240892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402200101
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