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Switching desaturase enzyme specificity by alternate subcellular targeting

The functionality, substrate specificity, and regiospecificity of enzymes typically evolve by the accumulation of mutations in the catalytic portion of the enzyme until new properties arise. However, emerging evidence suggests enzyme functionality can also be influenced by metabolic context. When th...

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Autors principals: Heilmann, Ingo, Pidkowich, Mark S., Girke, Thomas, Shanklin, John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478599/
https://ncbi.nlm.nih.gov/pubmed/15240892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402200101
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