Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

BACKGROUND: Diamond–Blackfan anemia (DBA) was the first ribosomopathy associated with mutations in ribosome protein (RP) genes. The clinical phenotypes of DBA include failure of erythropoiesis, congenital anomalies and cancer predisposition. Mutations in RPL5 are reported in approximately 9 ~ 21 % o...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Wan, Yang, Zhang, Qian, Zhang, Zhaojun, Song, Binfeng, Wang, Xiaomin, Zhang, Yingchi, Jia, Qiong, Cheng, Tao, Zhu, Xiaofan, Leung, Anskar Yu-Hung, Yuan, Weiping, Jia, Haibo, Fang, Xiangdong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785739/
https://ncbi.nlm.nih.gov/pubmed/26961822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0174-9
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