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Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

BACKGROUND: Diamond–Blackfan anemia (DBA) was the first ribosomopathy associated with mutations in ribosome protein (RP) genes. The clinical phenotypes of DBA include failure of erythropoiesis, congenital anomalies and cancer predisposition. Mutations in RPL5 are reported in approximately 9 ~ 21 % o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Med Genomics
Main Authors: Wan, Yang, Zhang, Qian, Zhang, Zhaojun, Song, Binfeng, Wang, Xiaomin, Zhang, Yingchi, Jia, Qiong, Cheng, Tao, Zhu, Xiaofan, Leung, Anskar Yu-Hung, Yuan, Weiping, Jia, Haibo, Fang, Xiangdong
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785739/
https://ncbi.nlm.nih.gov/pubmed/26961822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0174-9
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