Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing

BACKGROUND: Diamond–Blackfan anemia is a rare congenital red blood cell dysplasia that develops soon after birth. RPL11 mutations account for approximately 4.8% of human DBA cases with defective hematopoietic phenotypes. However, the mechanisms by which RPL11 regulates hematopoiesis in DBA remain el...

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Main Authors: Zhang, Zhaojun, Jia, Haibo, Zhang, Qian, Wan, Yang, Zhou, Yang, Jia, Qiong, Zhang, Wanguang, Yuan, Weiping, Cheng, Tao, Zhu, Xiaofan, Fang, Xiangdong
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890587/
https://ncbi.nlm.nih.gov/pubmed/24341334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-896
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