Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

BACKGROUND: Diamond–Blackfan anemia (DBA) was the first ribosomopathy associated with mutations in ribosome protein (RP) genes. The clinical phenotypes of DBA include failure of erythropoiesis, congenital anomalies and cancer predisposition. Mutations in RPL5 are reported in approximately 9 ~ 21 % o...

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Bibliografiska uppgifter
I publikationen:BMC Med Genomics
Huvudupphovsmän: Wan, Yang, Zhang, Qian, Zhang, Zhaojun, Song, Binfeng, Wang, Xiaomin, Zhang, Yingchi, Jia, Qiong, Cheng, Tao, Zhu, Xiaofan, Leung, Anskar Yu-Hung, Yuan, Weiping, Jia, Haibo, Fang, Xiangdong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785739/
https://ncbi.nlm.nih.gov/pubmed/26961822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0174-9
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