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A novel PCCB mutation in a Thai patient with propionic acidemia identified by exome sequencing

Propionic acidemia (PA) is an inborn error of metabolism, caused by mutations in either the PCCA or PCCB gene, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here we report a 6-year-old Thai boy with PA who was born to consanguineous parents. Exome sequencing identified...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genome Var
Hauptverfasser: Porntaveetus, Thantrira, Srichomthong, Chalurmpon, Suphapeetiporn, Kanya, Shotelersuk, Vorasuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785532/
https://ncbi.nlm.nih.gov/pubmed/27081542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2015.33
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