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A novel PCCB mutation in a Thai patient with propionic acidemia identified by exome sequencing

Propionic acidemia (PA) is an inborn error of metabolism, caused by mutations in either the PCCA or PCCB gene, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here we report a 6-year-old Thai boy with PA who was born to consanguineous parents. Exome sequencing identified...

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Библиографические подробности
Опубликовано в: :Hum Genome Var
Главные авторы: Porntaveetus, Thantrira, Srichomthong, Chalurmpon, Suphapeetiporn, Kanya, Shotelersuk, Vorasuk
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785532/
https://ncbi.nlm.nih.gov/pubmed/27081542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2015.33
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