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A novel PCCB mutation in a Thai patient with propionic acidemia identified by exome sequencing

Propionic acidemia (PA) is an inborn error of metabolism, caused by mutations in either the PCCA or PCCB gene, leading to mitochondrial accumulation of propionyl-CoA and its by-products. Here we report a 6-year-old Thai boy with PA who was born to consanguineous parents. Exome sequencing identified...

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Detalhes bibliográficos
Publicado no:Hum Genome Var
Main Authors: Porntaveetus, Thantrira, Srichomthong, Chalurmpon, Suphapeetiporn, Kanya, Shotelersuk, Vorasuk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785532/
https://ncbi.nlm.nih.gov/pubmed/27081542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2015.33
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