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Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel

Microglial activation is implicated in the pathogenesis of Parkinson’s disease (PD). Although the etiology of PD remains unclear, age and male gender are known PD risk factors. By comparing microglia and dopaminergic (DA) neurons in the substantia nigra (SN) of male and female mice of different ages...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Wu, Shih-Ying, Chen, Yun-Wen, Tsai, Sheng-Feng, Wu, Sheng-Nan, Shih, Yao-Hsiang, Jiang-Shieh, Ya-Fen, Yang, Ting-Ting, Kuo, Yu-Min
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785403/
https://ncbi.nlm.nih.gov/pubmed/26960267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22864
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