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Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel
Microglial activation is implicated in the pathogenesis of Parkinson’s disease (PD). Although the etiology of PD remains unclear, age and male gender are known PD risk factors. By comparing microglia and dopaminergic (DA) neurons in the substantia nigra (SN) of male and female mice of different ages...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4785403/ https://ncbi.nlm.nih.gov/pubmed/26960267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22864 |
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