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A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia

We have studied drug-response associated (DRA) gene expressions by applying a systems biology framework to the Cancer Cell Line Encyclopedia data. More than 4,000 genes are inferred to be DRA for at least one drug, while the number of DRA genes for each drug varies dramatically from almost 0 to 1,22...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Liu, Xiaoming, Yang, Jiasheng, Zhang, Yi, Fang, Yun, Wang, Fayou, Wang, Jun, Zheng, Xiaoqi, Yang, Jialiang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785360/
https://ncbi.nlm.nih.gov/pubmed/26960563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22811
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