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A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia

We have studied drug-response associated (DRA) gene expressions by applying a systems biology framework to the Cancer Cell Line Encyclopedia data. More than 4,000 genes are inferred to be DRA for at least one drug, while the number of DRA genes for each drug varies dramatically from almost 0 to 1,22...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Xiaoming, Yang, Jiasheng, Zhang, Yi, Fang, Yun, Wang, Fayou, Wang, Jun, Zheng, Xiaoqi, Yang, Jialiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785360/
https://ncbi.nlm.nih.gov/pubmed/26960563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22811
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