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Anticancer drug sensitivity prediction in cell lines from baseline gene expression through recursive feature selection

BACKGROUND: An enduring challenge in personalized medicine is to select right drug for individual patients. Testing drugs on patients in large clinical trials is one way to assess their efficacy and toxicity, but it is impractical to test hundreds of drugs currently under development. Therefore the...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Dong, Zuoli, Zhang, Naiqian, Li, Chun, Wang, Haiyun, Fang, Yun, Wang, Jun, Zheng, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485860/
https://ncbi.nlm.nih.gov/pubmed/26121976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1492-6
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