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Anticancer drug sensitivity prediction in cell lines from baseline gene expression through recursive feature selection

BACKGROUND: An enduring challenge in personalized medicine is to select right drug for individual patients. Testing drugs on patients in large clinical trials is one way to assess their efficacy and toxicity, but it is impractical to test hundreds of drugs currently under development. Therefore the...

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發表在:BMC Cancer
Main Authors: Dong, Zuoli, Zhang, Naiqian, Li, Chun, Wang, Haiyun, Fang, Yun, Wang, Jun, Zheng, Xiaoqi
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485860/
https://ncbi.nlm.nih.gov/pubmed/26121976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1492-6
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