Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice

Late-onset hypogonadism (i.e. androgen deficiency) raises the risk for abdominal obesity in men. The mechanism for this obesity is unclear. Here, we demonstrated that hypogonadism after castration caused abdominal obesity in high-fat diet (HFD)-fed, but not in standard diet (SD)-fed, C57BL/6J mice....

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Publicado en:Sci Rep
Main Authors: Harada, Naoki, Hanaoka, Ryo, Horiuchi, Hiroko, Kitakaze, Tomoya, Mitani, Takakazu, Inui, Hiroshi, Yamaji, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785334/
https://ncbi.nlm.nih.gov/pubmed/26961573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23001
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