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Coordinated Action of Hypoxia-inducible Factor-1α and β-Catenin in Androgen Receptor Signaling

The androgen receptor (AR) acts as a ligand-dependent transcriptional factor and plays a critical role in the development and progression of androgen-dependent and castration-resistant prostate cancer. Castration results in hypoxia in prostate cancer cells, and hypoxia enhances transcriptional activ...

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Bibliografske podrobnosti
Main Authors: Mitani, Takakazu, Harada, Naoki, Nakano, Yoshihisa, Inui, Hiroshi, Yamaji, Ryoichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460458/
https://ncbi.nlm.nih.gov/pubmed/22865883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388298
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