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Coordinated Action of Hypoxia-inducible Factor-1α and β-Catenin in Androgen Receptor Signaling
The androgen receptor (AR) acts as a ligand-dependent transcriptional factor and plays a critical role in the development and progression of androgen-dependent and castration-resistant prostate cancer. Castration results in hypoxia in prostate cancer cells, and hypoxia enhances transcriptional activ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460458/ https://ncbi.nlm.nih.gov/pubmed/22865883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388298 |
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