Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice

Late-onset hypogonadism (i.e. androgen deficiency) raises the risk for abdominal obesity in men. The mechanism for this obesity is unclear. Here, we demonstrated that hypogonadism after castration caused abdominal obesity in high-fat diet (HFD)-fed, but not in standard diet (SD)-fed, C57BL/6J mice....

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Bibliographic Details
Published in:Sci Rep
Main Authors: Harada, Naoki, Hanaoka, Ryo, Horiuchi, Hiroko, Kitakaze, Tomoya, Mitani, Takakazu, Inui, Hiroshi, Yamaji, Ryoichi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785334/
https://ncbi.nlm.nih.gov/pubmed/26961573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23001
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