Androgen deprivation causes truncation of the C‐terminal region of androgen receptor in human prostate cancer LNCaP cells

The androgen receptor (AR) acts as a ligand‐dependent transcription factor, whereas mutant AR lacking the C‐terminal ligand‐binding domain functions in a ligand‐independent manner. In the present study we report that the C‐terminal truncated AR, which we named AR‐NH1 (the N‐terminal fragment of AR c...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Harada, Naoki, Inoue, Kaoru, Yamaji, Ryoichi, Nakano, Yoshihisa, Inui, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685070/
https://ncbi.nlm.nih.gov/pubmed/22360658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02250.x
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