Novel Azasterols as Potential Agents for Treatment of Leishmaniasis and Trypanosomiasis

This paper describes the design and evaluation of novel azasterols as potential compounds for the treatment of leishmaniasis and other diseases caused by trypanosomatid parasites. Azasterols are a known class of (S)-adenosyl-l-methionine: Δ(24)-sterol methyltransferase(24-SMT) inhibitors in fungi, p...

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Autori principali: Lorente, Silvia Orenes, Rodrigues, Juliany C. F., Jiménez, Carmen Jiménez, Joyce-Menekse, Miranda, Rodrigues, Carlos, Croft, Simon L., Yardley, Vanessa, de Luca-Fradley, Kate, Ruiz-Pérez, Luis M., Urbina, Julio, de Souza, Wanderley, Pacanowska, Dolores González, Gilbert, Ian H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Susceptibility
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC478520/
https://ncbi.nlm.nih.gov/pubmed/15273104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2937-2950.2004
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