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Effect of methotrexate exposure at late gestation on development of telencephalon in rat fetal brain

Pregnant rats were treated with 30 mg/kg of methotrexate (MTX) on gestation day (GD) 16, and fetal brains were examined time-dependently. On GD 20, the appearance of the telencephalon in the MTX group was different from that in the control group, and the major axis of the telencephalon of the MTX gr...

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Bibliografske podrobnosti
izdano v:J Vet Med Sci
Main Authors: HIRAKO, Ayano, FURUKAWA, Satoshi, TAKEUCHI, Takashi, SUGIYAMA, Akihiko
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Veterinary Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785109/
https://ncbi.nlm.nih.gov/pubmed/26369365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.15-0389
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