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Effect of methotrexate on rostral migratory stream in newborn rats

Two-day-old rats were treated with subcutaneous injections of methotrexate (MTX) 5 mg/kg and 150 mg/kg, and their rostral migratory streams (RMS) were examined time-dependently. MTX treatment increased pyknotic and TUNEL-positive cells and decreased mitotic and phospho-Histone H3-positive cells at a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Med Sci
Hauptverfasser: HIRAKO, Ayano, SUN, Jin, FURUKAWA, Satoshi, TAKEUCHI, Takashi, SUGIYAMA, Akihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Veterinary Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710711/
https://ncbi.nlm.nih.gov/pubmed/26136044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.15-0280
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