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Effect of methotrexate exposure at middle gestation on the inner plate of the ocular cup and lens in the rat fetus
Pregnant rats were treated intraperitoneally with a single dose of methotrexate (MTX) 90 mg/kg on gestation day (GD) 13, and fetal eyeballs were examined time-dependently from GD 13.5 to 15.5. Throughout the experimental period, the inner plate of the ocular cup in the MTX group was significantly th...
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| Publicado no: | J Toxicol Pathol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Japanese Society of Toxicologic Pathology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958615/ https://ncbi.nlm.nih.gov/pubmed/27559242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0014 |
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