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Effect of methotrexate on cerebellar development in infant rats

Six-day-old rats were treated intraperitoneal injections with methotrexate 1 mg/kg, and the cerebellum was examined. Both the length and width of the vermis decreased in the methotrexate-treated group instead of the control from 4 day after treatment (DAT) onward. A significant reduction in the widt...

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Détails bibliographiques
Publié dans:J Vet Med Sci
Auteurs principaux: SUGIYAMA, Akihiko, SUN, Jing, UEDA, Kota, FURUKAWA, Satoshi, TAKEUCHI, Takashi
Format: Artigo
Langue:Inglês
Publié: The Japanese Society of Veterinary Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527500/
https://ncbi.nlm.nih.gov/pubmed/25754651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.14-0475
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