DNMT3b modulates melanoma growth by controlling levels of mTORC2 component RICTOR

DNA methyltransferase DNMT3B is frequently overexpressed in tumor cells and plays important roles during the formation and progression of several cancer types. However, the specific signaling pathways controlled by DNMT3B in cancers, including melanoma, are poorly understood. Here, we report that DN...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Micevic, Goran, Muthusamy, Viswanathan, Damsky, William, Theodosakis, Nicholas, Liu, Xiaoni, Meeth, Katrina, Wingrove, Emily, Santhanakrishnan, Manjula, Bosenberg, Marcus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785087/
https://ncbi.nlm.nih.gov/pubmed/26923591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.010
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