Wird geladen...

UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 Mouse Melanoma Model

Human melanomas exhibit relatively high somatic mutation burden compared to other malignancies. These somatic mutations may produce neoantigens that are recognized by the immune system, leading to an anti-tumor response. By irradiating a parental mouse melanoma cell line carrying three driver mutati...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pigment Cell Melanoma Res
Hauptverfasser: Wang, Jake, Perry, Curtis Jamison, Meeth, Katrina, Thakral, Durga, Damsky, William, Micevic, Goran, Kaech, Susan, Blenman, Kim, Bosenberg, Marcus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820096/
https://ncbi.nlm.nih.gov/pubmed/28379630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12591
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!