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UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 Mouse Melanoma Model
Human melanomas exhibit relatively high somatic mutation burden compared to other malignancies. These somatic mutations may produce neoantigens that are recognized by the immune system, leading to an anti-tumor response. By irradiating a parental mouse melanoma cell line carrying three driver mutati...
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| Publicado no: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820096/ https://ncbi.nlm.nih.gov/pubmed/28379630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12591 |
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