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PD-L1 methylation regulates PD-L1 expression and is associated with melanoma survival

The aim of this study is to determine the significance of programmed death-ligand 1 (PD-L1 or CD274) methylation in relation to PD-L1 expression and survival in melanoma. Despite the clinical importance of therapies targeting the PD-1/PD-L1 immune checkpoint in melanoma, factors regulating PD-L1 exp...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Micevic, Goran, Thakral, Durga, McGeary, Meaghan, Bosenberg, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475614/
https://ncbi.nlm.nih.gov/pubmed/30343532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12745
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