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Identification of an Inhibitor of the Aminoglycoside 6′-N-Acetyltransferase type Ib [AAC(6′)-Ib] by Glide Molecular Docking
The aminoglycoside 6’-N-acetyltransferase type Ib, AAC(6’)-Ib, confers resistance to clinically relevant aminoglycosides and is the most widely distributed enzyme among AAC(6’)-I-producing Gram-negative pathogens. An alternative to counter the action of this enzyme is the development of inhibitors....
Tallennettuna:
| Julkaisussa: | Medchemcomm |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4784703/ https://ncbi.nlm.nih.gov/pubmed/26973774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5MD00316D |
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