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Effects of F171 Mutations in the 6′-N-Acetyltransferase Type Ib [AAC(6′)-Ib] Enzyme on Susceptibility to Aminoglycosides

Substitutions at position F171 of 6′-N-acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme.

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Détails bibliographiques
Auteurs principaux: Chavideh, Ramona, Sholly, Steven, Panaite, Doina, Tolmasky, Marcelo E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC89568/
https://ncbi.nlm.nih.gov/pubmed/10543772
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