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Effects of F171 Mutations in the 6′-N-Acetyltransferase Type Ib [AAC(6′)-Ib] Enzyme on Susceptibility to Aminoglycosides

Substitutions at position F171 of 6′-N-acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme.

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Chavideh, Ramona, Sholly, Steven, Panaite, Doina, Tolmasky, Marcelo E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10543772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.11.2811
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