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Using selenomethionyl derivatives to assign sequence in low-resolution structures of the AP2 clathrin adaptor

Selenomethionine incorporation is a powerful technique for assigning sequence to regions of electron density at low resolution. Genetic introduction of methionine point mutations and the subsequent preparation and crystallization of selenomethionyl derivatives permits unambiguous sequence assignment...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr D Struct Biol
Main Authors: Kelly, Bernard T., Graham, Stephen C., Owen, David J.
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784665/
https://ncbi.nlm.nih.gov/pubmed/26960121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798315021580
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