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Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles

Clathrin-mediated endocytosis (CME) is crucial for modulating the protein composition of a cell’s plasma membrane. Clathrin forms a cage-like, polyhedral outer scaffold around a vesicle, to which cargo-selecting clathrin adaptors are attached. Adaptor protein complex (AP2) is the key adaptor in CME....

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Kovtun, Oleksiy, Dickson, Veronica Kane, Kelly, Bernard T., Owen, David J., Briggs, John A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375805/
https://ncbi.nlm.nih.gov/pubmed/32743075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba8381
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