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LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP
The production of the proinflammatory cytokines TNF-α and IL-6 is regulated by various mRNA-binding proteins, influencing stability and translation of the respective transcripts. Research in macrophages has shown the importance of the p38-MK2-tristetraprolin (TTP) axis for regulation of TNF-α mRNA s...
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| Publicado en: | Cell Signal |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4784419/ https://ncbi.nlm.nih.gov/pubmed/23499908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.02.022 |
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