Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

BACKGROUND: Mast cells participate in immune responses by releasing potent immune system modifiers via degranulation. Due to currently reported controversial roles of mast cells in Streptococcus pneumoniae infections, this study aimed to determine the role and mechanism of mast cells in clearing S. ...

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Publicado no:World Allergy Organ J
Main Authors: Yang, Jing, Wang, Jichao, Zhang, Xuemei, Qiu, Yulan, Yan, Jurong, Sun, Si, He, Yujuan, Yin, Yibing, Xu, Wenchun
Formato: Artigo
Idioma:Inglês
Publicado em: World Allergy Organization 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479162/
https://ncbi.nlm.nih.gov/pubmed/31044024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.waojou.2019.100028
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