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Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis often leads to severe cellular defects finally interfering with contractile function. Here, we analyze for the first time the role of Atrogin-1, a muscle-specific E3 ubiquiti...
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Publicado no: | Int J Mol Sci |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783921/ https://ncbi.nlm.nih.gov/pubmed/26840306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020187 |
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