Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia

The main objective of this study was to compare the physiological changes (withdrawal and corneal reflexes, respiratory and cardiac frequency, blood oxygen saturation, and rectal temperature) following intraperitoneal administration of ketamine (80 mg/kg) and xylazine (10 mg/kg) to 3-, 6-, 12- and 1...

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Detaylı Bibliyografya
Yayımlandı:Exp Anim
Asıl Yazarlar: Giroux, Marie-Chantal, Santamaria, Raphael, Hélie, Pierre, Burns, Patrick, Beaudry, Francis, Vachon, Pascal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Japanese Association for Laboratory Animal Science 2015
Konular:
Original
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783652/
https://ncbi.nlm.nih.gov/pubmed/26489361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.15-0039
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