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Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12- and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia

The main objective of this study was to compare the physiological changes (withdrawal and corneal reflexes, respiratory and cardiac frequency, blood oxygen saturation, and rectal temperature) following intraperitoneal administration of ketamine (80 mg/kg) and xylazine (10 mg/kg) to 3-, 6-, 12- and 1...

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書誌詳細
出版年:Exp Anim
主要な著者: Giroux, Marie-Chantal, Santamaria, Raphael, Hélie, Pierre, Burns, Patrick, Beaudry, Francis, Vachon, Pascal
フォーマット: Artigo
言語:Inglês
出版事項: Japanese Association for Laboratory Animal Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783652/
https://ncbi.nlm.nih.gov/pubmed/26489361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.15-0039
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