Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia

While the cage refinement is a necessary step towards improving the welfare of research rats, increasing the complexity and surface area of the living space of an animal may have physiological impacts that need to be taken into consideration. In this study, ketamine (80 mg/kg) and xylazine (10 mg/kg...

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Bibliografiske detaljer
Udgivet i:Exp Anim
Main Authors: Dodelet-Devillers, Aurore, Zullian, Chiara, Beaudry, Francis, Gourdon, Jim, Chevrette, Julie, Hélie, Pierre, Vachon, Pascal
Format: Artigo
Sprog:Inglês
Udgivet: Japanese Association for Laboratory Animal Science 2016
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Original
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111841/
https://ncbi.nlm.nih.gov/pubmed/27263962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.16-0026
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