Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ(1−42)

Aberrant increases in neuronal network excitability may contribute to the cognitive deficits in Alzheimer's disease (AD). However, the mechanisms underlying hyperexcitability are not fully understood. Such overexcitation of neuronal networks has been detected in the brains of APP/PS1 mice. In t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Neurosci
Päätekijät: Wang, Xi, Zhang, Xiao-Gang, Zhou, Ting-Ting, Li, Na, Jang, Chun-Yan, Xiao, Zhi-Cheng, Ma, Quan-Hong, Li, Shao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2016
Aiheet:
Psychiatry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783403/
https://ncbi.nlm.nih.gov/pubmed/27013956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00094
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