Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

Hutchinson–Gilford progeria syndrome (HGPS), a fatal premature aging disease, is caused by a single‐nucleotide mutation in the LMNA gene. Previous reports have focused on nuclear phenotypes in HGPS cells, yet the potential contribution of the mitochondria, a key player in normal aging, remains uncle...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Xiong, Zheng‐Mei, Choi, Ji Young, Wang, Kun, Zhang, Haoyue, Tariq, Zeshan, Wu, Di, Ko, Eunae, LaDana, Christina, Sesaki, Hiromi, Cao, Kan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783354/
https://ncbi.nlm.nih.gov/pubmed/26663466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12434
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