Defects in MAP1S‐mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed

Autophagy is a cellular process that executes the turnover of dysfunctional organelles and misfolded or abnormally aggregated proteins. Microtubule‐associated protein MAP1S interacts with autophagy marker LC3 and positively regulates autophagy flux. LC3 binds with fibronectin mRNA and facilitates it...

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Vydáno v:Aging Cell
Hlavní autoři: Li, Wenjiao, Zou, Jing, Yue, Fei, Song, Kun, Chen, Qi, McKeehan, Wallace L., Wang, Fen, Xu, Guibin, Huang, Hai, Yi, Jinglin, Liu, Leyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783353/
https://ncbi.nlm.nih.gov/pubmed/26750654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12441
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