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Autophagy Enhanced by Microtubule and Mitochondrion-associated MAP1S Suppresses Genome Instability and Hepatocarcinogenesis

Dysfunctional autophagy is associated with tumorigenesis, yet the relationship between the two processes remains unclear. Here, we show that MAP1S levels immediately become elevated in response to diethylnitrosamine-induced or genome instability-driven metabolic stress in a murine model of hepatocar...

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Hlavní autoři: Xie, Rui, Wang, Fen, McKeehan, Wallace L., Liu, Leyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242898/
https://ncbi.nlm.nih.gov/pubmed/22037873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2170
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