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Autophagy Enhanced by Microtubule and Mitochondrion-associated MAP1S Suppresses Genome Instability and Hepatocarcinogenesis

Dysfunctional autophagy is associated with tumorigenesis, yet the relationship between the two processes remains unclear. Here, we show that MAP1S levels immediately become elevated in response to diethylnitrosamine-induced or genome instability-driven metabolic stress in a murine model of hepatocar...

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Detalhes bibliográficos
Main Authors: Xie, Rui, Wang, Fen, McKeehan, Wallace L., Liu, Leyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242898/
https://ncbi.nlm.nih.gov/pubmed/22037873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2170
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