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CD19 controls TLR9 responses in human B cells
BACKGROUND: CD19 is a B-cell specific molecule that serves as a major co-stimulatory molecule for amplifying B cell receptor (BCR) responses. Bi-allelic CD19 gene mutations cause common variable immunodeficiency (CVID) in humans. BCR and TLR9 induced B-cell responses are impaired in most CVID patien...
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| Udgivet i: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783287/ https://ncbi.nlm.nih.gov/pubmed/26478008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.08.040 |
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