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TLR7 and TLR9 responsive human B cells share phenotypic and genetic characteristics

B cells activated by nucleic-acid sensing Toll-like receptor 7 and TLR9 proliferate and secrete immune globulins. Memory B cells are presumably more responsive due to higher TLR expression levels, but selectivity and differential outcomes remain largely unknown. In this study, peripheral blood human...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Simchoni, Noa, Cunningham-Rundles, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369401/
https://ncbi.nlm.nih.gov/pubmed/25740945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402690
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