FEASIBILITY OF RADIOLABELED SMALL MOLECULE PERMEABILITY AS A QUANTITATIVE MEASURE OF MICROBICIDE CANDIDATE TOXICITY

OBJECTIVE: To determine the feasibility of using quantitative changes in vaginal permeability to small molecules as a measure of candidate microbicide toxicity. STUDY DESIGN: Controlled, open-labeled, prospective study. Seven healthy women received a single vaginal dose of hydroxyethylcellulose gel...

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Detalhes bibliográficos
Publicado no:Contraception
Main Authors: Coleman, Jenell, Fuchs, Edward, Aung, Wutyi S., Marzinke, Mark A., Bakshi, Rahul P., Spiegel, Hans M.L., Robinson, Jennifer, Hendrix, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783221/
https://ncbi.nlm.nih.gov/pubmed/26772905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2016.01.002
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